IADR Abstract Archives

Phenotypic Characteristics Affecting Cardiovascular Disorders in Obstructive Sleep Apnea Patients

Objectives: Based on our knowledge, there is no documented data about the role of severity of Obstructive Sleep Apnea(OSA) as a cause of Cardiovascular Disorders(CVD) in patients who have OSA, among Iranian population. This study aims to obtain comprehensive information about this relationship and the effect of phenotypic characteristics on it.

Methods: In a cross sectional study, we studied patients had OSA with 5 or more Apnea/Hypopnea Index (AHI) who referred to Noor  Sleep Clinic , Tehran, Iran. Severity of OSA, and other data were collected from Polysomnography reports and patient`s files. Patients were divided into CVD - and CVD+ groups.

Results: In CVD- group, 76% of patients were male, mean severity of OSA was 36.86 ± 29.54 (AHI), mean age was 44.80 ± 10.10 years, mean BMI was 29.03 ±  4.76 Kg/m2 , percentage of smoker patients was 14.8% and 60.0% of patients had university education. In CVD+ group, 60.8% of patients were male, mean severity of apnea was 49.93±30.22 (AHI), mean age was 56.20±9.55 years, mean BMI was 31.78±5.64 Kg/m2 , percentage of smoker patients was 8.8% and 52.3% of patients had university education. Multi variable analyses showed that, odds ratio for one grade  increase in BMI and 1 year increase of age were 1.13 and 1.12 respectively (P_ value  < 0.001). In presence of this variables, severity of apnea, gender and education had no significant relation with CVD (P_ value respectively: 0.36, 0.83, 0.79 ).

Conclusions: We concluded that in our study, BMI and aging have the strongest relationship with CVD. So communication health care programmers should consider BMI control and improve diagnostic and treatment equipment for aged patients.

Division: Iranian Division Meeting
Meeting: 2011 Iranian Division Meeting (Tehran, Iran)
Location: Tehran, Iran
Year: 2011
Final Presentation ID: 122
Abstract Category|Abstract Category(s): Scientific Groups
Authors
  • Shirani, Gholamreza  ( Tehran University of Medical Sciences, Tehran, N/A, Iran )
  • Morovati, Seyyede Pouya  ( Shahid Beheshti University of Medical Sciences, Tehran, N/A, Iran )
  • SESSION INFORMATION
    Oral Session
    Oral and Maxillofacial Surgery and Periodontal Research
    12/30/2011