introducing an effective way inorder to use LLL as a stimulate factore in osteosynthesis with xenograft bone materials(Bio-Oss) for bone defect healing.
Methods:
12 new Zealand white rabbits in two groups of six for this study were selected.four defects created in each rabbit calvarium.the first defect left empty as control.lasr used for second defect,third defect was files by Bio-Oss and the fourth defect filled by Bio-Oss and irradiate by laser.the irradiated defects were subjected to the first irradiation immediately after surgery befor flap closure and it was repeated every other day for 3 weeks.the firstgroup was killed in 4 weeks and the second group were sacrified in 8 weeks.Histological and histomorphometric analysis were performed on samples.
Results: the expriment has shown that inflammation,foreign body reaction and vitality in both 4 and 8 weeks were not statistically significant.there was no difference in amount of bone formation between all samples in 4 and 8 weeks.
Conclusions: results of this study has shown that LLL increase bone formation effectively,but the amount of bone formation in 4 weeks(early healing period)is more sensational significantly.