Methods: The study was a clinical trial (in vivo) and used a split mouth design. A total of 23 pairs of bilateral leathery primary root caries were selected from Shahid Beheshti Dental School patients. After brushing by wet brush and cleaning the lesions DIAGNODENT values of samples were recorded in three points. Half of the samples which had been randomly selected were treated by 12 seconds of ozone with OZOTOP (MECTRON SWISS Inc.) Opposite arch were selected as control group. Fluoride therapy on both groups performed And DIAGNODENT values were measured again. This process was repeated a month later and DIAGNODENT values recorded. 3 months after initial treatment DIAGNODENT values were measured again. Results were evaluated by using paired t Test.
Results: The highest reduction was observed within the group of combined Using of fluoride and ozone after 3 months (2.04) which is significantly different with control. And the least change was observed in the group of immediately after the first treatment with fluoride (0.27).
Conclusions:
The combined effect of fluoride and ozone in reducing the DIAGNODENT Value is more than using fluoride alone in a 3 months period.