Methods: The study population included unilateral alveolar cleft patients (n=16). The patients were assigned into grafting with iliac in combination with PRGF. All operations were carried out by the same surgeon. The outcome was measured six month later as the proportion of the remaining to the pre-surgery cleft volume. Statistical analysis was done by Two Way ANOVA and Paired t-test.
Results: The mean age of the patients was 15 years old; about half of them being male (55%). The mean pre-surgery cleft volume was 1.67 cm3 and mean remaining bone volume was 1.14 cm3. The age of grafting and baseline cleft volume were not related to the success of graft.
Conclusions: The study revealed the benefits of application of growth factors in alveolar cleft repair to achieve the optimum surgery results.