Association Between Oral Lichen Planus and Helicobacter Pylori Infection
Objectives: Lichen planus is a common inflammatory mucocutaneous disease. Etiology of lichen planus is unknown but many factors such as Helicobacter pylori are suggested as risk factors for lichen planus. This study was performed to evaluate the relationship between H. pylori infection and oral lichen planus.
Methods: In this study, 41 patients with oral lichen planus and 82 sex-age matched healthy controls without any kind of mucocutaneous diseases were included. The level of anti H. pylori antibody (IgG) was measured in the serum using ELISA method.
Results: Patients with oral lichen planus had a lower prevalence of anti H. pylori antibody (IgG) compared to controls (65.9% vs 51.2%) but this difference was not significant.
Conclusions: There was not a significant difference in Anti H.pylori IgG seropositivity between cases and controls.