Methods: 30 mandibular molars with grade II furcation involvement in 30 patients were treated. Test sites received autogenous bone graft and PRGF, while control sites were treated with autogenous bone graft only. Clinical parameters included: clinical probing depth (CPD), vertical clinical attachment level (v-CAL), horizontal clinical attachment level (h-CAL), location of the gingival margin. (LGM), surgical exposed horizontal probing depth of bony defect (E-HPD), vertical depth of bone crest (v-DBC), vertical depth of the base of bony defect (v-DBD), and length of intrabony defect (LID). After 6 months, patients underwent re-entry surgery in order to evaluate the results. All data were analyzed using SPSS 14 software, and statistical tests Kolmogrov, mann U whitney and paried t test were used.
Results: After 6 months, both treatment approaches led to significant improvements in v-CAL and h-CAL, and a significant decrease in CPD, E-HPD, v-DBD and LID. There was no significant difference between LGM and V-DBC in the two treatment groups compared to baseline. Also, there was no significant difference in any of the parameters between the study groups.
Conclusion: Based on the results of this study, application of PRGF in treatment of furcation involvement with bone graft does not provide any clinical enhancement in the therapeutic outcomes, but further research is necessary.
Key words: Furcation, Furcation involvement, Autogenous bone graft, Plasma rich growth factors.