Comparison of different chelating agents (EDTA and RC-Prep) on apical microleakage of root canals prepared by MTwo rotary system
Objectives: The aim of the present study was to determine the effects of different chelating agents on apical microleakage following canal preparation by MTwo rotary system. Methods: In this experimental in-vitro study, 66 single-canal human teeth with a root length of approximately 10±1 mm were selected. Samples were randomly divided into 3 experimental groups (n=20) and 2 control groups (n=3). Samples were prepared using MTwo rotary system and using RC-Prep + 2.6% NaOCl in Group A, EDTA + 2.6% NaOCl in Group B, and saline alone in group C. Then, they were kept in the dye for 72 hours in room temperature. Tooth clearing method examined apical microleakage, and stereomicroscope served to evaluate dye penetration. Results: Apical microleakage in RC-Prep group was the lowest (P<0.05). No significant difference was found between EDTA and normal saline groups (P=0.165). Conclusions: The use of RC-Prep chelators seems to be more effective compared to EDTA in reducing the apical microleakage when sodium hypocolorite is used as an irrigant.