Effectiveness of Carisolv-2 in Comparison with NaOCl and Ca(OH)2
Objectives: The main effect of Carsiolv-2 in chemo-mechanical caries removal depends on its high pH of 11 due to the containing NaOCl (0.5%). Therefore, the aim of this study was to compare the effectiveness of Carsiov-2 with two other alkaline substances used in dentistry: NaOCl and Ca(OH)2. Methods: 60 extracted teeth (stored in PBS buffer) were split in the middle of a carious lesion. The 120 specimens were randomly divided in 3 groups. In group I one half of a cavity was excavated with NaOCl (0.5%, pH 11.7), the corresponding half with Ca(OH)2 (pH 12.4) (Calxyl, OCO, Dirmstein, Germany), in group II with NaOCl and Carisolv-2 (Biolin, Sävedalen, Sweden) and in group III with Ca(OH)2 and Carisolv-2 (n=20 in each case) by using Carisolv-hand-instruments. Subsequently, histological specimens were produced from all cavities and analysed by light-microscope after Mallory-Azan-staining. The thickness of remaining caries was measured (<1mm or >1mm). The data were statistically evaluated using the Chi-square-test. Results: In group I 50.5% of the specimens treated with NaOCl and 48.7% treated with Ca(OH)2, respectively, were evaluated to be caries-free. The results in group II were NaOCl 61.5% and Carisolv-2 75.4% caries-free, and in group III Ca(OH)2 61.2% and Carisolv-2 73.9%. No statistically significant differences were obtained between NaOCl- and Ca(OH)2-excavation (group I: p=0.89). Compared to NaOCl and Ca(OH)2 Carisolv-2 showed significant better results for chemo-mechanically caries removal (groups II + III: p<0.05). In NaOCl- and Ca(OH)2-treated specimens carious layers with a thickness >1mm were found significantly more often than in the Carisolv-2 treated specimens (groups II + III: p<0.05), whereas there were no differences between NaOCl- and Ca(OH)2–excavation (p=0.06). Conclusion: Carisolv-2 is more effective in chemo-mechanical caries removal than NaOCl or Ca(OH)2.