IADR Abstract Archives
Bone Repair by Human Demineralized Dentin Matrix Scaffold and Concentrated Growth Factor
Objectives: New materiales introduced in regenerative dentistry
New technique for enhancement of bone repair
Methods: Ten adult male rabbits (weight 2 to 2.5 kg) were used in this study. In each rabbit two holes were created (one in each tibia). In rabbits, one hole was left empty as control and the second was packed with HDDM and CGF.
Results: Bone repair occurred faster in the graft group when compared to the control group. Osteoid tissue formation was seen at the bone defect at one week in the graft group, and osseous tissue formation was seen filling the bone defects at 6 weeks. the new bone showed better organization than control group and most of the formed osteons were fully compacted.
Conclusions: Combining Human Demineralized Dentin Scaffold (HDDS) with concentrated growth factor (CGF) improved graft biomaterial when used as xenograft and it became more effective by inducing a high level of new bone formation.
New technique for enhancement of bone repair
Methods: Ten adult male rabbits (weight 2 to 2.5 kg) were used in this study. In each rabbit two holes were created (one in each tibia). In rabbits, one hole was left empty as control and the second was packed with HDDM and CGF.
Results: Bone repair occurred faster in the graft group when compared to the control group. Osteoid tissue formation was seen at the bone defect at one week in the graft group, and osseous tissue formation was seen filling the bone defects at 6 weeks. the new bone showed better organization than control group and most of the formed osteons were fully compacted.
Conclusions: Combining Human Demineralized Dentin Scaffold (HDDS) with concentrated growth factor (CGF) improved graft biomaterial when used as xenograft and it became more effective by inducing a high level of new bone formation.
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