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TNF-á in Epithelial cells infected with Candida albicans

Objective: To investigate the change of tumor necrosis factor a,(TNF-a) in oral epithelial cells (KB cells) infected with candida albicans.

Methods: Two-site ELISA and RT-PCR were applied to determine the levels of TNF-aprotein or mRNA expression in the KB cells respectively .

Results: Candida albicans can induce the KB cells secrete TNF-a. The tendency of the TNF-aprotein secreted by KB cells rised with the time but did not change when candida albicans was more.

Conclusions: Candida albicans is responsible for the oral epithelial cells express and product TNF-a.


Division: Chinese Division Meeting
Meeting: 2007 Chinese Division Meeting (Xi'an, China)
Location: Xi'an, China
Year: 2007
Final Presentation ID:
Abstract Category|Abstract Category(s): Scientific Groups
Authors
  • Zhang, Ling  ( China Medical Univercity, shenyang,liaoning, N/A, China )
    • SESSION INFORMATION
    Oral Session
    Oral Medicine & Pathology