IADR Abstract Archives

Induction of Traumatic TMJ Ankylosis in Growing Rats

Objectives: The purpose of this study was to determine the role of the damage in condylar cartilage and disc in the induction of traumatic temporomandibular joint (TMJ) ankylosis in the growing period.

Methods: The present experimental study was performed in growing rats by a common condyle fracture model accompanying with damage in disc and condylar cartilage (experimental group,n=12),and the sham-operated growing rats was as the control group(n=10). Two rats in experimental group were sacrificed 24 hours after operation, and the result following surgical intervention was observed. Each rat's body weight in two groups was monitored and recorded at 1 week, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 10 weeks and 12 weeks after operation. At 12 weeks after the operation, the animals were sacrificed and the prognosis in the two groups was compared by mandible deviation measure, body weight evaluation,X-ray examination and histological observation.

Results: All animals in control group showed normal body weight increase, and none of them has abnormal histopathological change in the articular and condylar tissue. However, animals from the experimental group present slow body weight increase and obvious mandible deviation, and all involved TMJs show fibrous ankylosis in various degrees.

Conclusion: The damage to the condylar cartilage and disc in condylar fracture may play important role in the development of traumatic TMJ ankylosis in growing period.


Division: Chinese Division Meeting
Meeting: 2007 Chinese Division Meeting (Xi'an, China)
Location: Xi'an, China
Year: 2007
Final Presentation ID:
Abstract Category|Abstract Category(s): Scientific Groups
Authors
  • Li, Zhi  ( Key Lab for Oral Biomedical Engineering of the Ministry of Eduction,School and Hospital of Stomatology, Wuhan University, Wuhan, N/A, China )
  • Li, Zu-bing  ( Key Lab for Oral Biomedical Engineering of the Ministry of Eduction,School and Hospital of Stomatology, Wuhan University, Wuhan, N/A, China )
  • Li, Jin-rong  ( Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, N/A, )
  • SESSION INFORMATION
    Oral Session
    Oral & Maxillofacial Surgery