Periodontal tissue conditions' relationship to homocysteine level in peripheral blood

Objectives: To investigate the relationship between the conditions of periodontal tissue and homocysteine level of peripheral blood. Methods: 60 persons who had different periodontal tissue conditions were under investigation. All cases had no systemic diseases and received no antibiotics within 3 months. All cases received periodontal examination and plaque index (PLI), bleeding index (BI), probing depth (PD) and attachment loss (AL) were recorded. Meanwhile the blood specimens of all cases were collected and HCY level of peripheral blood was examined. Finally the relationships of HCY level to data of periodontal tissue were statistically analyzed. Results: Significantly different HCY levels (F=56.743, P=0.000)were found among the group with no or slight AL (8.82±2.80), the group of moderate AL (11.43±1.81) and the group of severe AL (20.35±4.10). HCY level in peripheral blood had high correlation to AL, PLI, PD and BI(R=0.905,0.636,0.795,0.696 respectively and P=0.000). Conclusions: The conditions of periodontal tissue have high correlation to the HCY level in peripheral blood. And the severer the deterioration of periodontal tissue is, the higher the HCY level in peripheral blood becomes .