Periodontal tissue conditions' relationship to CRP level in peripheral blood

Objectives: to research on the relationship between the conditions of periodontal tissue and C-reactive protein(CRP) level in peripheral blood. Methods: 60 persons who had different periodontal tissue conditions were under investigation. All cases had no systemic diseases and taken no antibiotics within 3 months. All cases received periodontal examination and then data such as plaque index (PLI), bleeding index (BI), probing depth (PD) and attachment loss (AL) were collected. Meanwhile, the blood specimens of all cases were collected and CRP level of peripheral blood was examined. Finally, 60 cases were divided into three group according to the degree of AL, that is, group of no or slight AL(AL°Ü2mm), group of moderate AL (2mm3mm). Both CRP levels among groups of different AL and the relationships of CRP level to data of periodontal tissue conditions were statistically analyzed. Results: there were significantly different CRP levels among the group of no or slight AL, the group of moderate AL and the group of severe AL (AL=1.66±0.74mm, 3.04±0.49mm 7.12±2.61mm respectively, F=56.743, P=0.000 ). CRP level in peripheral blood had high correlation to AL, PLI, PD and BI(R=0.911,0.783,0.768,0.764 respectively, P=0.000). Conclusion: The conditions of periodontal tissue have high correlation to the CRP level in peripheral blood. And with the deterioration of periodontal tissue conditions, the CRP level in peripheral blood becomes high.