Effect of perioglas filling defective alveolar bone on tooth movement

Objectives:To observe the movement of rats' tooth on the area of defective alveolar bone filled with perioglas, and conpared with contralateral tooth, to evaluate objectively if there is rats' tooth movement in the area of defective alveolar bone filled with perioglas and if statistical differences is presented in the distance of rats' tooth movement between bilateral maxillary first molar. Methods: Forty female 6-week-old SPF Wister rats were selected. they were locally anesthetized with 2% Nocaine on the mesial area of maxillary right first molar where hole was bored with dynamo fissure bur. Perioglas was placed into the hole. If the area filled with perioglas had osteogenesis completely, orthodontic appliances were fixed to mesially guide the maxillary first molar. Vuttingdisc and histologic slice were made to measure the bilateral maxillary first molar movement distances and to study the periodontal tissues histologically. Results: The area filled with perioglas presented uniform osseous tissue which binded normal bone with bone tissue. The rats' tooth can mesially move in the area filled with perioglas. There was no significant difference between the two sides of the first molar movement distance and the periodontal tissues histologically with pair-matched t test (P>0.05). Conclusions: The rats' tooth can mesially move in the area filled with perioglas. There were no significant differences in the distance of tooth movement and the remodeling of powered periodontal tissue between the area filled with perioglas and the contralateral side.