IADR Abstract Archives

Performance of a copper-containing adhesive in a cariogenic oral environment

Objectives: To evaluate the effect of the incorporation of copper nanoparticles (CuNp) into a universal adhesive on the antimicrobial activity (AMA), bond strength (µTBS), nanoleakage (NL), elastic modulus (EM) and nanohardness (NH) of the resin-dentin interfaces, at 24 h (24h) and after in situ cariogenic challenge (CC).
Methods: CuNp (0% [control] and 0.1 wt%) were added in a universal adhesive. After enamel removal, the adhesives were applied to dentine surfaces. Each restored tooth was longitudinally sectioned to obtain two hemi-teeth; one of them was evaluated after 24h and the other was included in an intra-oral palatal device placed in the mouth of ten volunteers for 14 days in CC. After that, each hemi-tooth was removed and oral biofilm formed was collected. The AMA was evaluated against Streptococcus mutans. For 24h and CC groups, each hemi-tooth was sectioned in “x” direction to obtain one slice for each EM/NH evaluation. The remains of each hemi-tooth were sectioned in “x” and "y" direction to obtain resin-dentin beams for µTBS and NL evaluation (24h and CC). ANOVA and Tukey’s test were applied (α=0.05).
Results: The presence of CuNp significantly improved AMA as well as all properties evaluated (24h; p<0.05). Although a decrease in the adhesive properties (µTBS/NL) for all groups after CC (p<0.05) occurred, the incorporation of CuNp maintained NH/EM values after CC (p<0.05).
Conclusions: The addition of 0.1% CuNp in an adhesive may be an alternative to provide antimicrobial activity and increase its bonding and mechanical properties, even under a cariogenic challenge. This is the first in situ study proving that the incorporation of CuNp in a universal adhesive is a achievable alternative to provide antimicrobial properties and improved integrity of the hybrid layer under in situ cariogenic challenge.

2021 Chilean Division Annual Meeting (Virtual) 2021

2021

Dental Materials 5: Biocompatibility, Bioengineering and Biologic Effects of Materials
  • Gutierrez, Felipe  ( Universidad de los Andes , Santiago , Región Metropolitana , Chile ;  Universidad Finis Terrae , Santiago , Región Metropolitana , Chile )
  • Ñaupari-villasante, Romina  ( State University of Ponta Grossa , Ponta Grossa , Paraná , Brazil )
  • De Paris Matos, Thalita  ( State University of Ponta Grossa , Ponta Grossa , Paraná , Brazil )
  • Núñez, Alejandra  ( State University of Ponta Grossa , Ponta Grossa , Paraná , Brazil )
  • Méndez-bauer, Luján  ( State University of Ponta Grossa , Ponta Grossa , Paraná , Brazil )
  • Sutil, Elisama  ( State University of Ponta Grossa , Ponta Grossa , Paraná , Brazil )
  • Loguercio, Alessandro  ( State University of Ponta Grossa , Ponta Grossa , Paraná , Brazil )
  • NONE
    Poster Session
    Posters 2