IADR Abstract Archives
The Regional Acceleratory Phenomenon in Tooth Movement: Role of Saliva
Objectives: In current orthodontics, it is accepted to perform maneuvers to accelerate dental movement, including microosteoperforations (MOPs). Xerostomia is a pathology that affects a significant part of the population and is linked to multiple causes. In adults, this situation can modify the response to treatment with MOPs. Animal studies conducted in our laboratory showed that hyposialia delays healing of bone tissue, also alters the biomechanical properties of the maxila by increasing bone stiffness and maximum fracture load, as well as the density of the alveolar bone repaired after 30 days post- extraction. Objetive To assess the effect of submandibulectomy (SMx) in the early stages of tooth movement (MD) accelerated with MOPs therapy at 7 days.
Methods: Materials and Methods 48 male Wistar rats 200-250gr were divided into 8 groups Control (C), MOPs, experimental Orthodontics (O) y O+MOPs; and the same four groups subjected to SMx. Nickel-titanium closed-coil springs exerting a 50g force (T0) were secured from maxillary incisors to first molars for tooth movement. Three MOPs were performed mesial of the maxillary first molars using a 1/4 bur at low speed. The SMx was performed one week before T0. Animals were euthanized 7 days after T0. Tooth movement was determined as the distance from mesial of the first molar to the alveolar bone crest of de incisors with a digital caliper (mm). Results were analyzed with one way ANOVA and Tukeys post test (p<0.05).
Results: Results After 7 days of treatment, greater tooth movement was observed in group O+MOPs+SMx(10.43±0.05) vs. O+MOPs(10.88±0.09; p<0.05), y vs. O+SMx (10.84±0.05, p<0,05). However, no statistically significant differences were observed between the groups O(10.81±0.2) vs O+MOPS.
Conclusions: Conclusion The state of hyposialia conditions the MD, probably due to an increase in the inflammatory response induce by MOPs therapy.
Methods: Materials and Methods 48 male Wistar rats 200-250gr were divided into 8 groups Control (C), MOPs, experimental Orthodontics (O) y O+MOPs; and the same four groups subjected to SMx. Nickel-titanium closed-coil springs exerting a 50g force (T0) were secured from maxillary incisors to first molars for tooth movement. Three MOPs were performed mesial of the maxillary first molars using a 1/4 bur at low speed. The SMx was performed one week before T0. Animals were euthanized 7 days after T0. Tooth movement was determined as the distance from mesial of the first molar to the alveolar bone crest of de incisors with a digital caliper (mm). Results were analyzed with one way ANOVA and Tukeys post test (p<0.05).
Results: Results After 7 days of treatment, greater tooth movement was observed in group O+MOPs+SMx(10.43±0.05) vs. O+MOPs(10.88±0.09; p<0.05), y vs. O+SMx (10.84±0.05, p<0,05). However, no statistically significant differences were observed between the groups O(10.81±0.2) vs O+MOPS.
Conclusions: Conclusion The state of hyposialia conditions the MD, probably due to an increase in the inflammatory response induce by MOPs therapy.