IADR Abstract Archives
Alzheimer's And Periodontitis: How Are They Related? A Systematic Review. .
Objectives: To analyze the relationship between Alzheimer Disease (AD) and Periodontitis.
Methods: Systematic Review was performing, based in the methodology of the Cochrane Manual and PRISMA declaration. The search strategy used was the following: “Alzheimer” and “Periodontitis” as key concepts; ScienceDirect, Pubmed and Scielo as databases; searching without year restriction. The inclusion criteria were: Clinical Trials, Cases and Control studies that describe the relationship between Alzheimer and Periodontitis in human patients. The exclusion criteria were: Bibliographic reviews, animal studies.
Results: 1177 articles were found after the first search. After title/ abstract revision, 10 articles met the study objetives. After the full reading of these articles, 6 articles met the inclusion criteria and were analyzed. 5 articles were added after reading the bibliography of 6 articles previous included. In general terms, the articles determined through case-control studies that the development of periodontitis is strongly related to the cognitive deterioration suffered by patients with AD in which the decrease in their motor, communicative and cognitive functions lead to a loss of the habit and concern for oral hygiene. In particular analysis patients with AD, have an average probing depth of 3.6, while healthy patients average 1.6, Furthermore, these patients have a higher prevalence of Periodontitis than healthy patients.
Conclusions: Patients with AD for to their condition and cognitive impairment are more susceptible to develop periodontitis. However, it must be considered that due to the age of the patients with AD, other factors could be contributing to the development of Periodontitis, such as polypharmacy and systemic diseases. Nevertheless These patients must have greater observation and follow-up by the dentists.
Methods: Systematic Review was performing, based in the methodology of the Cochrane Manual and PRISMA declaration. The search strategy used was the following: “Alzheimer” and “Periodontitis” as key concepts; ScienceDirect, Pubmed and Scielo as databases; searching without year restriction. The inclusion criteria were: Clinical Trials, Cases and Control studies that describe the relationship between Alzheimer and Periodontitis in human patients. The exclusion criteria were: Bibliographic reviews, animal studies.
Results: 1177 articles were found after the first search. After title/ abstract revision, 10 articles met the study objetives. After the full reading of these articles, 6 articles met the inclusion criteria and were analyzed. 5 articles were added after reading the bibliography of 6 articles previous included. In general terms, the articles determined through case-control studies that the development of periodontitis is strongly related to the cognitive deterioration suffered by patients with AD in which the decrease in their motor, communicative and cognitive functions lead to a loss of the habit and concern for oral hygiene. In particular analysis patients with AD, have an average probing depth of 3.6, while healthy patients average 1.6, Furthermore, these patients have a higher prevalence of Periodontitis than healthy patients.
Conclusions: Patients with AD for to their condition and cognitive impairment are more susceptible to develop periodontitis. However, it must be considered that due to the age of the patients with AD, other factors could be contributing to the development of Periodontitis, such as polypharmacy and systemic diseases. Nevertheless These patients must have greater observation and follow-up by the dentists.