Micro-osteoperforations: Acceleration of Orthodontic Tooth Movement In Animal Model

Objectives: Determine if the use of Micro-osteoperforations (MOPs) is effective in the acceleration of orthodontic tooth movement (OTM).
Methods: A total of 16 32-week-old male Sprague-Dawley rats were analyzed, who were fitted with orthodontic appliances in the upper jaw and were grouped according to research day on days 7, 14, 21 and 28 (t1-t2-t3-t4). The Force was applied through a Nitilol coil located between the upper first molar and the upper central incisor, using a force of 25 grams. The left side was subjected to OTM and MOPs of 1 mm depth at an anterior distance of 5 mm from the molar to be mesialized, and was analyzed and compared with the right side, where only conventional OTM was applied. Wilcoxon non-parametric statistical tests for related samples were used to analyze the differences in the distribution of data between the two groups. The level of statistical significance used for the interpretation of results was 5%.
Results: In the first two weeks, the left side had greater movement and speed compared to the right side, however, from day 21 there was a slowdown in movement on the experimental side, while the control side achieved greater speed and movement . None of the changes was statistically significant.
Conclusions: The treatment with MOPs is able to increase the speed of the OTM in rats during the first three weeks after applying the stimulus, but it is not statistically significant in short periods of time. Periodic drilling is necessary to reactivate the Regional Acceleration Phenomenon.