IADR Abstract Archives
Nitrous Oxide Sedation Reduce Sessions And Cortisol Levels In Children.
Objectives: To assess the pharmacological effectiveness of nItrous oxide sedation (NOS) compared to cognitive behavioral therapy (CBT) in dental treatments of anxious children by evaluating the number of sessions and attention time required for dental discharge and psychometric and physiological parameters of anxiety.
Methods: A radomized clinical trial was designed in patients classified as anxious [Face Image Scale (FIS)] randomized in two groups: NOS (25 children, 6.44 ± 1.6 years; 70.83% men) treated with inhalation of gas mixture 10 -70%: 90-30% nitrous oxide: oxygen; and CBT group (24 children, 6.62 ± 2.01 age, 36% men). The number of sessions required for dental discharge and anxiety indices of children with FIS scale, FRANK scale and salivary cortisol levels (chi-square, T-test, two-way ANOVA and Sidak's test) were analyzed.
Results: For the dental discharge group NOS performed a total of 96 attentions (average 3.92 ± 2.33) versus CBT with 129 attentions (5.38 ± 2.68; p = 0.04). The FIS and FRANK scales were shown to decrease anxiety levels in both treatment groups. The NOS group presented at the beginning and at the end of the treatment lower expressions of the cortisol stress marker (mean 26.8 nmol / L) compared with CBT (mean 38.8 nmol / L; p = 0.04). According of number of chidren with treatment completed, the NOS showed a NNT = 2.39 (95% CI = 1.63-552)
Conclusions: The NOS has proven to be an effective treatment method in the comprehensive care of anxious pediatric pediatric patients and may be indicated as an alternative therapy to patients who do not respond to CBT conventional therapy.
Methods: A radomized clinical trial was designed in patients classified as anxious [Face Image Scale (FIS)] randomized in two groups: NOS (25 children, 6.44 ± 1.6 years; 70.83% men) treated with inhalation of gas mixture 10 -70%: 90-30% nitrous oxide: oxygen; and CBT group (24 children, 6.62 ± 2.01 age, 36% men). The number of sessions required for dental discharge and anxiety indices of children with FIS scale, FRANK scale and salivary cortisol levels (chi-square, T-test, two-way ANOVA and Sidak's test) were analyzed.
Results: For the dental discharge group NOS performed a total of 96 attentions (average 3.92 ± 2.33) versus CBT with 129 attentions (5.38 ± 2.68; p = 0.04). The FIS and FRANK scales were shown to decrease anxiety levels in both treatment groups. The NOS group presented at the beginning and at the end of the treatment lower expressions of the cortisol stress marker (mean 26.8 nmol / L) compared with CBT (mean 38.8 nmol / L; p = 0.04). According of number of chidren with treatment completed, the NOS showed a NNT = 2.39 (95% CI = 1.63-552)
Conclusions: The NOS has proven to be an effective treatment method in the comprehensive care of anxious pediatric pediatric patients and may be indicated as an alternative therapy to patients who do not respond to CBT conventional therapy.