BlueRemin and Silver Diamine Fluoride on artificial caries lesions

Objectives: To compare the effect of BlueRemin (BR) and Silver Diamine Fluoride (SDF) as remineralizing agent in enamel and dentin on artificial dental caries lesion through microhardness assay and microCT tests.
Methods: Material and methods: In vitro experimental study, using a microbiological caries lesion model described by Cahuana-Vásquez and Cury, 2010, was used. Third molar enamel and dentin were including in a biofilm of S. mutans (ATCC 33668, 10% saccharose) and then exposed to silver diamine fluoride and BlueRemin according to manufactures protocols of applications. Measurement of Vickers microhardness and mineral density through microCT were evaluated.
Results: Differences in mineral density and surface microhardness measured in enamel and dentin discs does not have significant difference between the enamel and dentin disc treated with BR and SDF.
Conclusions: Discussion: Application of BF and SDF helps re-mineralization of enamel and dentin discs, which could be a treatment for teeth with caries lesions. Further research is need to best understand the potential use of BR in clinical setting