Leucocytes-platelet Rich Fibrin As Adjuvant in Periodontal Treatment: Pilot Study
Objectives: To evaluate the effect of the use of Leucocytes-platelet rich fibrin (L-PRF) as an adjuvant to scaling and root planing in the periodontal clinical parameters and in the post-therapy hypersensitivity Methods: A randomized, blind, pilot clinical trial was carried out, in which 11 patients were recruited with periodontal pockets depths ≥6 mm, who received in a hemiarcade scaling and root planing + exudate irrigation + L-PRF (test) and in the contralateral scaling and root planing + irrigation with physiological saline (control). Periodontal clinical parameters were evaluated, at the beginning and at 6 weeks, in addition to post-therapy hypersensitivity using a visual analogue scale. The results were analyzed by descriptive statistics with measures of central tendency and dispersion
Results: The clinical variables analyzed presented differences in the group that received the L-PRF, however, the results were not statistically significant. The dentine hypersensitivity showed a statistically significant relevance, which obtained a p-value of 0.003 and 0.002, a week and 6 weeks, respectively Conclusions: The use of L-PRF reduce the post-therapy hypersensitivity compared to the group that did not receive L-PRF. Although there were improvements in most of the clinical parameters analyzed when the L-PRF was used, these did not present a statistical significance. More clinical trials and a larger sample size are required to confirm these observations