Correlation Between Glucose In Saliva And Glucose Intolerance Test (PTGO) In Pregnant Women. Higueras Hospital Talcahuano 2004.

There are studies suggesting a positive correlation between glucose in saliva and blood, with intolerance to glucose in diabetic patients. During pregnancy there are several metabolic and hormonal changes resulting in pathologies like intolerance to glucose or gestational diabetes. The purpose of this study was to establish the relationship between glicemia, glucose concentration on non stimulated saliva and PTGO test, for glucose intolerance. 41 women in their 6^th. to 8^th. month of pregnancy were controlled at Higueras Hospital in Talcahuano, between July and September of 2004.Non stimulated saliva was collected after glicemia test, and a short interview was applied to detect any other pathologic findings during pregnancy as well as some dental information ( DMFT index, sugar time and active caries).To determine glucose on saliva a GOD-POD assay was performed (color enzymatic assay of Oxidize Perodidase Glucose at 570nm). Thereafter a PTGO test was carried out.The glicemia levels showed an average of 81.51 mg/dL. PTGO test result showed a maximum of 162 mg/dL and a minimum of 71 mg/dL. 36 cases were found to have PTGO test greater than Glicemia. Glucose in saliva was between 29,2 mg/dL y 189,78 mg/dL with an average of 89,50mg/dL.The statistical analysis showed that Glicemia as well as glucose in saliva are directly related to PTGO (P=0,336; P=0,493; p<0,05). There was no significant statistical correlation between Glicemia and glucose on saliva.These results support the idea that high levels of glucose on saliva could be good indication of intolerance to glucose as PTGO test do. Also, high concentration of glucose in saliva could be favorable to the development of dental caries.    Fondo de Investigación Facultad de Odontología UDD