(1) To determine the initial hydrogen peroxide (HP) content of two at-home bleaching products and (2) to assess the in vitro HP release kinetics of these products.
Material and Methods:
The samples were divided into two groups: Group DW PH9,5% and Group DW PC38%, matching the products DayWhite ACP 9,5% and DayWhite ACP 38% (Discus Dental, USA). Each product was titrated for its HP content using a Cerium sulfate-based titration technique.
Using a peroxidase-based colorimetric method, samples were analyzed, after being applied according to the manufacturer’s instructions and over twice the manufacturer’s recommended application times (n=13- 20).
The results are indicated as Mean ± 95% Confidence Interval for mean of the percentage of HP present in the whitening product (w/w) and as milligrams of HP.
To test variables time, percentage and milligrams of HP release, Pearson correlation analysis was used, Paired Student t-test or ANOVA, as appropriate. A significance level of P<0,05 was used for statistical comparisons.
Results:
The bleaching products’ titrated concentration values were higher than the ones claimed by manufacturer, with significant differences in both products (P<0,05). These products reveal a similar release of HP. However, at respective recommend manufacturer’s time, DW PH9,5% released about 11,42mg (115%±6.88) of HP, and DW PC38% released about 6,17 mg (45%±2.76) of HP.
Conclusion:
At the manufacturer’s time, DW PH9,5% released all HP amount. Nevertheless, DW PC38% did not release the total amount of HP during the entire procedure. More studies of HP release kinetics in vivo for these two products are needed.