Method: 40 volunteers were divided into 2 groups. The first group was introduced to brush their teeth with Fluoride plus Arginine containing tooth paste and the second group was introduced to use Fluoride tooth paste twice a day. Visual analog score (VAS score) was used to record hypersensitivity score after applying tactile force and cold cotton pellet stimulation and then estimated personal perception. They were recalled for evaluation VAS score again after using toothpaste 4, 8 and 12 week.
Result: This study revealed that Fluoride plus Arginine containing tooth paste reduce sensitivity score at week 8 and 12 when use cold cotton pellet stimuli compared to baseline visit significantly (p<0.05), for tactile stimuli and volunteer’s personal perception Fluoride plus Arginine containing tooth paste significantly reduce sensitivity score at week 4, 8 and 12 compare with baseline visit (p<0.05). Fluoride plus Arginine containing tooth paste can reduce sensitivity score more than Fluoride containing tooth paste at week 4, 8 and 12 when use tactile stimuli and cold cotton pellet stimuli, at week 12 when use volunteer’s personal perception (p<0.05).
Conclusion: Collectively, our data shows that Fluoride plus Arginine containing tooth paste can reduce sensitivity score more than fluoride containing tooth paste