The aim of this study was to evaluate the mechanical and chemical properties of newly developed AIC.
Methods: Commercial glass ionomer sealant ((Fuji III™, GC Co., Tokyo, Japan) was the control and base material. Twenty eight weight percent of hydroxyapatite (HAp: spherical shaped HAP, Taihei Chemical Industrial, Inc., Osaka, Japan) was added into the glass ionomer powder. Specimens were fabricated the fractural strength and eluted fluoride ion concentration were measured. In addition, an antibacterial test for Streptococcus mutans ATCC25175 (S. mutans) was performed by the ATP luminescence method.
Results: The addition of HAp into GIC led to significantly higher strength after 1h, 24h and 1y from mixing and to significantly increase the fluoride release abilities of the cement. The luminescence intensity of S. mutans in culture fluid with AIC was significantly lower than that in culture fluid with control (P < 0.01).
Conclusion: These results indicate that AIC has higher antibacterial properties and may be effective in reducing caries progression by sealing it on the non-cavitated caries.
Acknowledgement: This research is being supported by JSPS Grant-in-Aid for Scientific Research (C) # 24592975.