IADR Abstract Archives

Application of epinephrine reduced articaine solution for routine dental treatment

Objectives: The use of epinephrine as a vasoconstrictor in dentistry is the gold standard. The effects after local application are increased efficacy, longer duration, reduced toxicity and ischemia at the treatment site. After resorption or intravascular injection side effects may occur. Especially in risk patients the amount of epinephrine is therefore still discussed.

Methods: In line with a non-interventional clinical study 908 patients were monitored with a 4 % solution of articaine and an epinephrine concentration of 1:400.000 (3M ESPE) for routine dental treatment (conservative, surgical, prosthetic) with an expected duration of approximately 30 minutes.

Results: 29.19 % of the patients had risk factors in their history, mostly cardiovascular diseases (15.4% total) and nearly all had a pharmacotherapy. Treated teeth were mainly tested sensitive (81.17 %) preoperatively and prepared for fillings or crowns. In 98.35 % the planned treatment was finished. Reasons for incomplete treatment were mostly technical or temporal problems, only one patient complained of insufficient anaesthesia. The mean injected volume was 1.3 + 0.49 ml and the depth of anaesthesia in 84.22 % complete, in 15.78 % sufficient. A second injection was necessary in 3.74 % before and in 11.89 % during treatment. 15 patients (1.7 %) complained about side effects, 6 of them immediately, 9 over the telephone the next day. Symptoms were unspecific reactions to the injection or local complications.

Conclusions: The epinephrine reduced solution is a safe and effective drug for routine dental treatment.

The non-interventional clinical study has been sponsored by 3M ESPE, Germany.


Continental European, Israeli, Scandinavian Divisions Meeting
2009 Continental European, Israeli, Scandinavian Divisions Meeting (Munich, Germany)
Munich Germany
2009
12
Symposium
  • Daubländer, Monika  ( University of Mainz, Mainz, N/A, Germany )
  • Willershausen, Brita  ( University of Mainz, Mainz, N/A, Germany )
  • Lauer, Hans-christoph  ( Johann Wolfgang Goethe-University Frankfurt, Frankfurt/Main, N/A, Germany )
  • Leckel, Michael  ( University of Heidelberg, Heidelberg, N/A, Germany )
  • Buff, Siegmar  ( Zahnarzt-Oralchirurgie, Wiesbaden, N/A, Germany )
  • Rösl, Benita  ( Zahnarztin, Neuhofen, N/A, Germany )
    • Symposium
    Local anaesthesia
    09/09/2009