Levels of some inflammatory markers has been found to be higher in individuals with periodontitis as compared to periodontally healthy controls, whereas levels of anti-inflammatory markers were lower. Following periodontal treatment, including preventive measures, it was shown that the local clinical signs of periodontal inflammatory burden were significantly reduced and the total body load of inflammation thus considerably decreased.
Provided a cause-relation effect of oral infection/inflammation to systemic diseases can be unquestionable established, preventive approaches to oral infection/inflammation also needs increased professional attention.