Charcot-Marie-Tooth Disease: a Case Report

Objectives: Charcot-Marie-Tooth (CMT) disease is characterized by hereditary motor and sensory neuropathy with muscle weakness, atrophy predominating in the lower extremities and rarely with dental findings. The aim of this case report is to present the dental findings of a patient with CMT disease.
Methods: A 9-year-old male patient referred to Ege University, Faculty of Dentistry, Department of Pedodontics with the complain of enamel-dentin fracture in his maxillary central incisor, caused by trauma. According to his anamnesis, he had no systemic disease. The clinical and radiographic examinations revealed that his maxillary central incisor was single and positioned on the midline without labial frenulum and the other maxillary central incisor was congenitally missing. In addition, the patient had caries at the primary molars and he had poor oral hygiene. After the esthetic restoration of incisor tooth with composite (GC G-aenial, Tokyo, Japan) and treatment of primary molars, the patient was referred to Ege University, Faculty of Medicine, Department of Medical Genetics, due to his dental findings. After his genetical analysis, he was diagnosed as Charcot-Marie-Tooth (CMT) hereditary neuropathy.
Results: The patient was undertaken to routine controls at the Departments of Pedodontics, Orthodontics and Medical Genetics at Ege University. He was followed up every 6 months at 3 years. During the recalls, special emphasis was given to the oral hygiene and motivation.
Conclusions: Genetic disorders are showing an upward trend and dentists have an important role at the diagnosis of these disorders according to the dental findings of their patients. Dentists should proceed their dental treatments with awareness.