IADR Abstract Archives
The Giant Cell Granulomas of the Jaws: Retrospective Pilot Study
Objectives: The purpose of this study was to investigate the patients who have central and peripheral giant cell granulomas of the jaws, analyse the treatment tecniques, and also recurrency rates.
Methods: Patients who applied to Hacettepe University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery in 2013-2023, with Giant Cell Lesions as a result of pathology were included in our study. Lesions size (horizontal, vertical, sagittal), recurrency and location, patient’s demographic data, cortical bone resorption and treatment tecniques were recorded.
Results: 15 patients were included in this study. Gender intense were at females (12 patients, %80), the average age was 39.9 and average follow-up periods was 5 years. 9 of 15 patients were peripheral, 6 of them central giant cell granuloma. The chronic diseases were determined in 4 patients. 9 lesions (%60) were seen at mandibula, 6 of them were in anterior side, 2 of them were in posterior side. Only one lesion was observed in both posterior and anterior side of right mandibula. 6 lesions (%40) were located at maxilla, 2 of them were in anterior side, 4 of them seen in posterior side. 6 of 15 patients (%40) had bone destruction. The avarage size of lesions were 2.0x1.6x1.1cm. The most prefered treatment method was curretage (11 patients, %73.3), however, reccurency was seen 4 of these patients (%36). 2 of 15 patients were treated with the combination of curretage and steroid injections, one of these lesions had recurrency. One patient were performed steroid injections, however, the lesion didn’t heal enough so systemic denosumab were applied.
Conclusions: Curretage was crucial treatment method for this lesions on the other hand reccurrency rate was %36 in this study. Larger sample size prospective and retrospective clinical studies are needed for the decision of the best treatment option.
Methods: Patients who applied to Hacettepe University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery in 2013-2023, with Giant Cell Lesions as a result of pathology were included in our study. Lesions size (horizontal, vertical, sagittal), recurrency and location, patient’s demographic data, cortical bone resorption and treatment tecniques were recorded.
Results: 15 patients were included in this study. Gender intense were at females (12 patients, %80), the average age was 39.9 and average follow-up periods was 5 years. 9 of 15 patients were peripheral, 6 of them central giant cell granuloma. The chronic diseases were determined in 4 patients. 9 lesions (%60) were seen at mandibula, 6 of them were in anterior side, 2 of them were in posterior side. Only one lesion was observed in both posterior and anterior side of right mandibula. 6 lesions (%40) were located at maxilla, 2 of them were in anterior side, 4 of them seen in posterior side. 6 of 15 patients (%40) had bone destruction. The avarage size of lesions were 2.0x1.6x1.1cm. The most prefered treatment method was curretage (11 patients, %73.3), however, reccurency was seen 4 of these patients (%36). 2 of 15 patients were treated with the combination of curretage and steroid injections, one of these lesions had recurrency. One patient were performed steroid injections, however, the lesion didn’t heal enough so systemic denosumab were applied.
Conclusions: Curretage was crucial treatment method for this lesions on the other hand reccurrency rate was %36 in this study. Larger sample size prospective and retrospective clinical studies are needed for the decision of the best treatment option.