IADR Abstract Archives
Investigation of Prevalence of HPV-Related Lesions in Oral Cavity
Objectives: WHO has recently reported that Human Papillomavirus (HPV)-related oral cancers will increase in several years. The aim of this study was to investigate the prevalence of HPV-related oral mucosal lesions at a university department.
Methods: Electronic search of database of Hacettepe University, was undertaken to identify patients with oral mucosal lesion and a biopsy report between 2012 and 2022. The biopsy reports including tentative diagnosis of “granuloma”, “papilloma”, “fibroma”, “condyloma acuminatum”, “verruca vulgaris”, “lipoma”, “leukoplakia”, “squamous papilloma”, “HPV” were investigated to detect HPV-related lesions. Patients who referred to Faculty of Dentistry, Department of Oral and Maxillofacial Surgery and whose biopsy reports were presented as HPV-related lesion were included in this study. A questionnaire was applied to these patients with teledentistry and patient’s gender, age, education level, the number of their children, systemic condition, family history and the occurrence of recurrent lesion were recorded.
Results: Total 4544 patients were screened. Possible HPV-related lesions were diagnosed in 24 patients. Squamous papilloma (10 patients, 41.7%), verruca vulgaris (3 patients, 12.5%), condyloma acuminatum (2 patients, 8.33%), papillomatous lesion (3 patients, 12.5%) were reported. Hyperkeratosis and acanthosis was reported in 6 patients. The prevalence of HPV was found 0.4%. All of 24 patients were called, but 8 males and 8 females with a mean age 42,9 years participated to the questionnaire. Nine patients was smoking, and 4 of 16 patients had alcohol use. The chronic diseases were determined in 11 patients. It was detected that none of married patients had a possible HPV-related lesion in their partners or children. Only 1 patient with squamous papilloma had recurrency.
Conclusions: The prevalence of HPV-related lesions in oral cavity was found to be low in this study, but multicenter studies with large sample size are needed to confirm the incidence of HPV in population.
Methods: Electronic search of database of Hacettepe University, was undertaken to identify patients with oral mucosal lesion and a biopsy report between 2012 and 2022. The biopsy reports including tentative diagnosis of “granuloma”, “papilloma”, “fibroma”, “condyloma acuminatum”, “verruca vulgaris”, “lipoma”, “leukoplakia”, “squamous papilloma”, “HPV” were investigated to detect HPV-related lesions. Patients who referred to Faculty of Dentistry, Department of Oral and Maxillofacial Surgery and whose biopsy reports were presented as HPV-related lesion were included in this study. A questionnaire was applied to these patients with teledentistry and patient’s gender, age, education level, the number of their children, systemic condition, family history and the occurrence of recurrent lesion were recorded.
Results: Total 4544 patients were screened. Possible HPV-related lesions were diagnosed in 24 patients. Squamous papilloma (10 patients, 41.7%), verruca vulgaris (3 patients, 12.5%), condyloma acuminatum (2 patients, 8.33%), papillomatous lesion (3 patients, 12.5%) were reported. Hyperkeratosis and acanthosis was reported in 6 patients. The prevalence of HPV was found 0.4%. All of 24 patients were called, but 8 males and 8 females with a mean age 42,9 years participated to the questionnaire. Nine patients was smoking, and 4 of 16 patients had alcohol use. The chronic diseases were determined in 11 patients. It was detected that none of married patients had a possible HPV-related lesion in their partners or children. Only 1 patient with squamous papilloma had recurrency.
Conclusions: The prevalence of HPV-related lesions in oral cavity was found to be low in this study, but multicenter studies with large sample size are needed to confirm the incidence of HPV in population.