IADR Abstract Archives
Evaluation of Active Magnesium-Containing-Toothpaste on Dental Plaque in Children
Objectives: Dental plaque is an archetypal biofilm of a complex microbial community found in the oral cavity. The aim of this randomized, double-blind and crossover study was to compare the plaque reduction efficacy of a newly developed toothpaste to a marketed active magnesium toothpaste with single-use brushing in children.
Methods: Forty healthy children aged 9–12-years-old were included in the study. The participants were asked not to eat for 4 hours and not to brush for 24 hours in advance of the test. In the first stage, the preliminary plaque in the children was recorded by the first researcher using plaque dye (Tri Plaque ID Gel, GC, Japan). After plaque disclosing the researcher brushed children's teeth with ROCS active magnesium toothpaste (DRC Group, Switzerland) for 1 minute with a standard toothbrush then the plaque staining was applied again. This procedure was repeated with Flouride toothpaste (Colgate Total, Palmolive, USA) according to crossover design after a washout period of 2 weeks. Dental plaque on the upper anterior incisors was photographed intra-orally before and after brushing under standardized conditions. These photographs were scored by using Turesky-Modified Quinley-Hein-Plaque-Index (TMQHPI) by two researchers (NKD, EAS) blinded to the groups. and inter-examiner reliability was assessed with Cohen’s Kappa test. Data analysis was performed using the Mann-Whitney-U and Wilcoxon-Test.
Results: The inter-examiner Kappa value was 0.85 (almost perfect). This randomized, double-blind, single-brushing, crossover study demonstrated both kinds of toothpaste showed statistically significant differences in TMQHPI scores immediately after single brushing when compared to baseline(p<0.001). There was a significant difference in TMQHPI plaque reductions between the toothpastes evaluated. Active magnesium toothpaste resulted in consistently and significantly(p<0.001) lower TMQHPI scores than Fluoride toothpaste.
Conclusions: Active magnesium toothpaste was found to be effective in reducing plaque when compared to Fluoride toothpaste with single-use brushing in children aged 9-12 years.
Methods: Forty healthy children aged 9–12-years-old were included in the study. The participants were asked not to eat for 4 hours and not to brush for 24 hours in advance of the test. In the first stage, the preliminary plaque in the children was recorded by the first researcher using plaque dye (Tri Plaque ID Gel, GC, Japan). After plaque disclosing the researcher brushed children's teeth with ROCS active magnesium toothpaste (DRC Group, Switzerland) for 1 minute with a standard toothbrush then the plaque staining was applied again. This procedure was repeated with Flouride toothpaste (Colgate Total, Palmolive, USA) according to crossover design after a washout period of 2 weeks. Dental plaque on the upper anterior incisors was photographed intra-orally before and after brushing under standardized conditions. These photographs were scored by using Turesky-Modified Quinley-Hein-Plaque-Index (TMQHPI) by two researchers (NKD, EAS) blinded to the groups. and inter-examiner reliability was assessed with Cohen’s Kappa test. Data analysis was performed using the Mann-Whitney-U and Wilcoxon-Test.
Results: The inter-examiner Kappa value was 0.85 (almost perfect). This randomized, double-blind, single-brushing, crossover study demonstrated both kinds of toothpaste showed statistically significant differences in TMQHPI scores immediately after single brushing when compared to baseline(p<0.001). There was a significant difference in TMQHPI plaque reductions between the toothpastes evaluated. Active magnesium toothpaste resulted in consistently and significantly(p<0.001) lower TMQHPI scores than Fluoride toothpaste.
Conclusions: Active magnesium toothpaste was found to be effective in reducing plaque when compared to Fluoride toothpaste with single-use brushing in children aged 9-12 years.