IADR Abstract Archives
Impact of Periodontitis and Erectile Dysfunction on Adverse Cardiovascular Event
Objectives: Our aim was to determine if the presence of periodontitis and erectile dysfunction has any effect on the incidence of major adverse cardiovascular events (MACEs).
Methods: A prospective study was performed on male patients that attended the Urology service. Erectile dysfunction was diagnosed according to the International Index of Erectile Function. Sociodemographic data were gathered and a complete periodontal examination was performed (pocket probing depth, clinical attachment loss, gingival bleeding index, plaque index and number of teeth) in each patient, and periodontitis was diagnosed according to the criteria by Lopez et al. The number of MACEs having occurred during the follow-up time as well as the number of the ones previous to follow-up were registered. Bivariate analyses, as well as a multivariate analysis, with general linear model using a Poisson-distribution, were performed, adjusting for age and previous diagnosis of cardiovascular disease.
Results: Information from 158 patients were collected over a maximum follow-up period of 6 years (mean follow-up = 4.2 years). A greater number of MACEs occurred in the group that presented periodontitis and erectile dysfunction (p=0.038) and also in the patients with previous diagnosis of cardiovascular disease, as expected. After adjusting by age and previous cardiovascular disease in the multivariate analysis, the annual MACE-event rate was estimated to be 3.7 times higher compared to the comparator group (p=0.049). Other periodontal clinical variables together with erectile dysfunction supported in tendency the results but were not statistically significant.
Conclusions: Patients jointly diagnosed with periodontitis and erectile dysfunction have a higher risk of suffering a major adverse cardiovascular event.
Methods: A prospective study was performed on male patients that attended the Urology service. Erectile dysfunction was diagnosed according to the International Index of Erectile Function. Sociodemographic data were gathered and a complete periodontal examination was performed (pocket probing depth, clinical attachment loss, gingival bleeding index, plaque index and number of teeth) in each patient, and periodontitis was diagnosed according to the criteria by Lopez et al. The number of MACEs having occurred during the follow-up time as well as the number of the ones previous to follow-up were registered. Bivariate analyses, as well as a multivariate analysis, with general linear model using a Poisson-distribution, were performed, adjusting for age and previous diagnosis of cardiovascular disease.
Results: Information from 158 patients were collected over a maximum follow-up period of 6 years (mean follow-up = 4.2 years). A greater number of MACEs occurred in the group that presented periodontitis and erectile dysfunction (p=0.038) and also in the patients with previous diagnosis of cardiovascular disease, as expected. After adjusting by age and previous cardiovascular disease in the multivariate analysis, the annual MACE-event rate was estimated to be 3.7 times higher compared to the comparator group (p=0.049). Other periodontal clinical variables together with erectile dysfunction supported in tendency the results but were not statistically significant.
Conclusions: Patients jointly diagnosed with periodontitis and erectile dysfunction have a higher risk of suffering a major adverse cardiovascular event.