IADR Abstract Archives
Systemic Perturbations Following Non-Surgical Periodontal Treatment in Hypertensive Patients.
Objectives: Both, periodontitis and hypertension are associated with systemic inflammation. The relationship between periodontal disease and increased blood pressure (BP) values is related to the production of systemic inflammation mediators. Therefore, the aim of this study was to evaluate the acute-phase response following the two different non-surgical periodontal treatment (NSPT) protocols in patients affected by hypertension and periodontitis, namely Full-Mouth Scaling and Root Planing (FM-SRP) and Quadrant Scaling and Root Planing (Q-SRP), respectively.
Methods: Forty consecutive patients affected by hypertension and periodontitis were enrolled in the study. The patients were randomly assigned to either FM-SRP or Q-SRP group. Periodontal parameters and BP values were measured at baseline, 1 and 90 days after the NSPT. Blood collection was performed at each timepoint in order to assess the level of high-sensitivity C-reactive protein (hs-CRP) levels.
Results: Periodontal treatment was successful in both treatment groups, exhibiting improvements in all periodontal parameters. Statistically significant difference between groups was found in hs-CRP levels increase 24-h after the treatment, with the FM-SRP group presenting remarkably higher values (p<0.05). Mean BP values showed a significant decrease 3-months after the treatment.
Conclusions: FM-SRP determines an acute systemic inflammation response in patients affected by hypertension and periodontitis, with a peak in hs-CRP levels 24-h after the NSPT. Periodontal treatment can produce a beneficial effect on blood pressure.
Methods: Forty consecutive patients affected by hypertension and periodontitis were enrolled in the study. The patients were randomly assigned to either FM-SRP or Q-SRP group. Periodontal parameters and BP values were measured at baseline, 1 and 90 days after the NSPT. Blood collection was performed at each timepoint in order to assess the level of high-sensitivity C-reactive protein (hs-CRP) levels.
Results: Periodontal treatment was successful in both treatment groups, exhibiting improvements in all periodontal parameters. Statistically significant difference between groups was found in hs-CRP levels increase 24-h after the treatment, with the FM-SRP group presenting remarkably higher values (p<0.05). Mean BP values showed a significant decrease 3-months after the treatment.
Conclusions: FM-SRP determines an acute systemic inflammation response in patients affected by hypertension and periodontitis, with a peak in hs-CRP levels 24-h after the NSPT. Periodontal treatment can produce a beneficial effect on blood pressure.