Bisphenol a Release From Orthodontic Composite Resins

Objectives: The purpose of this study was to evaluate and to quantify the release of bisphenol A from orthodontic composite resins after immersion in various media.
Methods: Resin samples (Blugloo, Grengloo, Transbond XT, Transbond LR) were cured for 20 seconds and immersed in distilled water, RPMI 1640 culture medium and ethanol for 24 hours. The eluates were extracted using solid phase extraction (SPE Bond Elut-NH₂) and then analyzed by gas phase chromatography and mass spectrometry with a quantification limit of 0.01 μg/mL.
Results: The lowest amount (0.19 μg/mL) of BPA released was observed in distilled water and the highest (1.75 μg/mL) in RPMI 1640 culture medium (table).
Conclusions: Orthodontic resins can release bisphenol A according to the immersion medium.