IADR Abstract Archives
The Spheno-Occipital Synchondrosis in Patients with Cleft Lip and Palate: A Case Control Study
Objectives: Growth of the spheno-occipital synchondrosis (SOS) influences the depth and height of the upper face, since it has a late ossification. Maturational age of a subject can be estimated by analyzing the fusion stage of the SOS. The literature suggests complete fusion for girls between 11 to 14 years and 13 to 16 years for boys. The aim of this study was to evaluate the differences in SOS fusion stage between patients with CLP and a control group, using cone beam computed tomography (CBCT) scans.
Methods: The study enrolled 125 patients, divided in CLP group (n=91, mean age 11,66 years) and control group (n=34, mean age 12,47 years). Each patients SOS was analyzed in a mid-sagital CBCT scan and the fusion stage assessed by using a 5-stage system. A Kolmogorov-Smirnov test was used to verify if there were statistically significant differences between the two groups, and a Kaplan-Meyer analysis to determine the median time to reach complete ossification of the SOS. Both groups were divided according to gender and the percentage of individuals in each stage was compared.
Results: No statistically significant differences were found either for boys (p=1.000) and girls (p=0.945). For boys, the median time of complete ossification was 15 years for both the CLP (IC95%[14.0, 16.0]) and control group (IC95%[14.2; 15.8]). There were no statistically significant differences between both groups (p=0.806). For girls, the median time of complete ossification was 14 years for the CLP group (IC95%[12.7, 15.3]) and 13 years for the control group (IC95%[11.9; 14.1]). There were no statistically significant differences between both groups (p=0.565).
Conclusions: Our data showed that the SOS fusion time is similar in patients with and without CLP, which may suggest that we apply the same orthodontic orthopedic protocol in patients with CLP.
Methods: The study enrolled 125 patients, divided in CLP group (n=91, mean age 11,66 years) and control group (n=34, mean age 12,47 years). Each patients SOS was analyzed in a mid-sagital CBCT scan and the fusion stage assessed by using a 5-stage system. A Kolmogorov-Smirnov test was used to verify if there were statistically significant differences between the two groups, and a Kaplan-Meyer analysis to determine the median time to reach complete ossification of the SOS. Both groups were divided according to gender and the percentage of individuals in each stage was compared.
Results: No statistically significant differences were found either for boys (p=1.000) and girls (p=0.945). For boys, the median time of complete ossification was 15 years for both the CLP (IC95%[14.0, 16.0]) and control group (IC95%[14.2; 15.8]). There were no statistically significant differences between both groups (p=0.806). For girls, the median time of complete ossification was 14 years for the CLP group (IC95%[12.7, 15.3]) and 13 years for the control group (IC95%[11.9; 14.1]). There were no statistically significant differences between both groups (p=0.565).
Conclusions: Our data showed that the SOS fusion time is similar in patients with and without CLP, which may suggest that we apply the same orthodontic orthopedic protocol in patients with CLP.