IADR Abstract Archives
Outcome of PRF Pulpotomy Using Different Calcium-silicate Based Materials in Permanent Molars with Irreversible Pulpitis: A randomized Controlled Trial
Objectives: To compare the clinical and radiographic outcomes of Platelet rich Fibrin (PRF) full pulpotmy after application of Biodentine, or Mineral trioxide aggregate (MTA), or Portland cement above PRF membrane.
Methods: Sixty permanent mandibular molars with carious exposure and symptoms of irreversible pulpitis were included in the study. Full pulpotomy was done, and then PRF was prepared and applied into the pulp chamber. The included teeth were randomly allocated to three groups according to the materials applied over the PRF; which were Biodentine, MTA, or Portland cement. Pain intensity was recorded using numeric rating scale score at baseline, 24 h, one week, one month, 3 month, 6 month and 12 month. Clinical and radiographic assessments were done every 3 months for one year. Cone beam computed tomography (CBCT) imaging was done immediately post operative, and after 12 months to evaluate the thickness of calcific bridge formed, and assess the periapical area.
Results: Clinical success rate was 100% at one week, 1 month, and 3 month, which dropped to 83.4% at 12 months. All three bioceramic materials were equally effective in providing pain relief after one week, one month, and three month follow-up periods, with no significant difference between them (P > 0.05 at all intervals). However,in the PRF with Portland cement group; 6.6% and 16.6% of the teeth showed slight widening of periodontal ligament space, and clinical signs and symptoms at 6 months and 12 months respectively . It was found in this study that there was no significance difference clinically between PRF with Biodentine group, and PRF with MTA group, but there was significance difference between PRF with Portland cement group, and the other two groups at 6, 12 months follow-up periods. Concerning the amount of calcific bridge formed, CBCT imaging showed that PRF with Biodentine group showed a significance difference when compared with the other two groups.
Conclusions: PRF Pulpotomy using Biodentine or MTA exhibited a high clinical success rate in mature molars with irreversible pulpitis.
Methods: Sixty permanent mandibular molars with carious exposure and symptoms of irreversible pulpitis were included in the study. Full pulpotomy was done, and then PRF was prepared and applied into the pulp chamber. The included teeth were randomly allocated to three groups according to the materials applied over the PRF; which were Biodentine, MTA, or Portland cement. Pain intensity was recorded using numeric rating scale score at baseline, 24 h, one week, one month, 3 month, 6 month and 12 month. Clinical and radiographic assessments were done every 3 months for one year. Cone beam computed tomography (CBCT) imaging was done immediately post operative, and after 12 months to evaluate the thickness of calcific bridge formed, and assess the periapical area.
Results: Clinical success rate was 100% at one week, 1 month, and 3 month, which dropped to 83.4% at 12 months. All three bioceramic materials were equally effective in providing pain relief after one week, one month, and three month follow-up periods, with no significant difference between them (P > 0.05 at all intervals). However,in the PRF with Portland cement group; 6.6% and 16.6% of the teeth showed slight widening of periodontal ligament space, and clinical signs and symptoms at 6 months and 12 months respectively . It was found in this study that there was no significance difference clinically between PRF with Biodentine group, and PRF with MTA group, but there was significance difference between PRF with Portland cement group, and the other two groups at 6, 12 months follow-up periods. Concerning the amount of calcific bridge formed, CBCT imaging showed that PRF with Biodentine group showed a significance difference when compared with the other two groups.
Conclusions: PRF Pulpotomy using Biodentine or MTA exhibited a high clinical success rate in mature molars with irreversible pulpitis.