IADR Abstract Archives
How to Reduce Dental Sensitivity?
Objectives: Dentine is an internal part of tooth owing numerous of tubules and usually covered by enamel. Tooth sensitivity is due to dentine exposure and stimuli transmission through tubules. One strategy to ameliorate tooth sensitivity is to block tubules by physical agent. Current questions are about ability to occlude over time and stability upon dietary acid challenge.
The aim of the present work is to present an experimental Solvay silica to reduce dental sensitivity through applicative tests.
Methods: Experimental silica has been formulated in a toothpaste containing abrasive and thickening silicas and tested by hydraulic conductance tests [1,2], to evaluate the degree of occlusion of human dentine (N=12) by flow reduction measurement. The resistance of treatment is evaluate with acid challenge application.
Results are compared to commercial toothpastes: 2 claiming tubule blocking properties and 2 without any sensitivity claims (N=6 to 12).
Statistic evaluation has been performed with one-way ANOVA and post-hoc Tukey test.
Solvay experimental silica and competitor tubule blocking silica (market benchmark) are applied on dentine samples and SEM pictures after treatment (N=4) help understand performances, before and after acid challenge.
Silica physico-chemical properties are characterized to establish silica structure- tubule occlusion properties relationships.
[1] Pashley, 1986
[2] Morawietz M., IADR 2017
Results: Hydraulic conductance results indicate that Solvay experimental silica provides a good level of tubules occlusion (80% of flow reduction), significantly higher than all negative controls and one positive control. Particularly a good level of occlusion after acid challenge is highlighted, compared to benchmark. SEM analyses after treatment support these results, confirming different action modes.
Coupled by physico-chemical characterizations, this study lets us conclude that the good performances can be explained by the unique properties of silica synthetized.
Conclusions: These results open new possibilities of formulations and silica development meeting current market requests on Oral Care for sensitivity.
The aim of the present work is to present an experimental Solvay silica to reduce dental sensitivity through applicative tests.
Methods: Experimental silica has been formulated in a toothpaste containing abrasive and thickening silicas and tested by hydraulic conductance tests [1,2], to evaluate the degree of occlusion of human dentine (N=12) by flow reduction measurement. The resistance of treatment is evaluate with acid challenge application.
Results are compared to commercial toothpastes: 2 claiming tubule blocking properties and 2 without any sensitivity claims (N=6 to 12).
Statistic evaluation has been performed with one-way ANOVA and post-hoc Tukey test.
Solvay experimental silica and competitor tubule blocking silica (market benchmark) are applied on dentine samples and SEM pictures after treatment (N=4) help understand performances, before and after acid challenge.
Silica physico-chemical properties are characterized to establish silica structure- tubule occlusion properties relationships.
[1] Pashley, 1986
[2] Morawietz M., IADR 2017
Results: Hydraulic conductance results indicate that Solvay experimental silica provides a good level of tubules occlusion (80% of flow reduction), significantly higher than all negative controls and one positive control. Particularly a good level of occlusion after acid challenge is highlighted, compared to benchmark. SEM analyses after treatment support these results, confirming different action modes.
Coupled by physico-chemical characterizations, this study lets us conclude that the good performances can be explained by the unique properties of silica synthetized.
Conclusions: These results open new possibilities of formulations and silica development meeting current market requests on Oral Care for sensitivity.
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