IADR Abstract Archives
Acute Effects of Vaping on General and Oral Hemodynamic Parameters.
Objectives: Little is known about the effects of electronic cigarettes (e-cigarettes) on oral mucosal blood flow. Previous studies indicated minimal impact of vaping on cardiovascular biomarkers. This study aims to investigate acute effects of e-cigarette use on general and oral hemodynamic parameters compared to the effects of conventional cigarettes (CC) and mouthpiece use.
Methods: A pilot clinical study was conducted among e-cigarette and CC users (n= 15, mean age 34.27 [SD=6.97] years, 66.7% male). Participants were allocated into three parallel groups based on their cigarette/e-cigarette use status: nicotine containing e-cigarette (n=5), conventional cigarette (n=5) and mouthpiece (n=5) user groups. Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (P) and palatinal mucosal blood flow were measured before (T1), immediately after (T2) and 15 minutes after (T3) the product was used. Two-way mixed ANOVA analyses were used to assess hemodynamic changes over time within and between groups.
Results: Although the main effect of groups and time were non-significant for any of the hemodynamic parameters, group×time interaction were significant for P (F(4)=5.45, p=.003) and marginally significant for DBP (F(4)=2.48, p=.071). The pattern of P change showed decreasing P over time among mouthpiece users, a moderate P increase for T2 and decrease for T3 among CC users, and a mild P increase for T2 followed by a decrease for T3 among e-cigarette users. The patterns of DBP changes showed moderate decrease for T2 and increase for T3 among both e-cigarette and mouthpiece users, while DPB increased for T2 and decreased for T3 among CC users. Palatinal mucosal perfusion decreased similarly from T2 to T3 in mouthpiece and CC user groups while increased among e-cigarette users, however between and within group differences were non-significant.
Conclusions: Acute effects of vaping on oral and general hemodynamic parameters were minimal in our study but sample size limitation should be considered.
Methods: A pilot clinical study was conducted among e-cigarette and CC users (n= 15, mean age 34.27 [SD=6.97] years, 66.7% male). Participants were allocated into three parallel groups based on their cigarette/e-cigarette use status: nicotine containing e-cigarette (n=5), conventional cigarette (n=5) and mouthpiece (n=5) user groups. Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (P) and palatinal mucosal blood flow were measured before (T1), immediately after (T2) and 15 minutes after (T3) the product was used. Two-way mixed ANOVA analyses were used to assess hemodynamic changes over time within and between groups.
Results: Although the main effect of groups and time were non-significant for any of the hemodynamic parameters, group×time interaction were significant for P (F(4)=5.45, p=.003) and marginally significant for DBP (F(4)=2.48, p=.071). The pattern of P change showed decreasing P over time among mouthpiece users, a moderate P increase for T2 and decrease for T3 among CC users, and a mild P increase for T2 followed by a decrease for T3 among e-cigarette users. The patterns of DBP changes showed moderate decrease for T2 and increase for T3 among both e-cigarette and mouthpiece users, while DPB increased for T2 and decreased for T3 among CC users. Palatinal mucosal perfusion decreased similarly from T2 to T3 in mouthpiece and CC user groups while increased among e-cigarette users, however between and within group differences were non-significant.
Conclusions: Acute effects of vaping on oral and general hemodynamic parameters were minimal in our study but sample size limitation should be considered.