IADR Abstract Archives
Pulpal Blood Flow of Iontophoresis 20% Lidocaine on carious dentine
Objectives:
To determine the effect of iontophoresis of 20% lidocaine with 1:1,000 epinephrine through carious dentine on pulpal blood flow and pulpal anesthesia in human subjects
Methods:
The experiments were carried out on 23 carious premolars or molars, planed to be restored with either class I, or class II restorations in 18 subjects (aged 18-25 yr., mean 21.5 yr.). The teeth were isolated with opaque black rubber dam and soft caries were removed. Then, the cavity was prepared with the airotor until the subject felt pain. The cavity was etched with 35% phosphoric acid for 10s. In group I, the cavity was filled with 20% lidocaine with 1:1,000 epinephrine. An iontophoretic device (Dentaphore-II model 611D, Life-tech, Inc.USA) was used with current 0.12–0.2 mA, 2 min., pain assessment was done. In group II, the experiments were performed exactly the same as group I, excepted distilled water was delivered with iontophoresis and pain sensation were assessed for 10 min. Pulpal blood flow (PBF) was recorded with a laser Doppler flowmeter (Periflux4001) before and after iontophoresis. The pain sensations induced by drilling, probing and air blast were assessed on 100 mm Visual analogue scale (VAS) before and after the treatments
Results: In group I (n=17), the PBF and mean VAS scores obtained at 2, 4, 6, 8, 10 min from all test stimuli were significantly decreased (P<0.05, 1-way RM ANOVA) after iontophoresis of lidocaine with epinephrine. In 16 teeth, the pulpal anesthesia was completely achieved within 0-10 min. In group II, distilled water iontophoresis produced no significant effect on the pain obtained from all stimuli (p>0.05, 1-way RM ANOVA on rank and Dunett’s test).
Conclusions: Iontophoretic application of 20% lidocaine with 1:1,000 epinephrine in carious human dentin could completely generate pulpal anesthesia.
To determine the effect of iontophoresis of 20% lidocaine with 1:1,000 epinephrine through carious dentine on pulpal blood flow and pulpal anesthesia in human subjects
Methods:
The experiments were carried out on 23 carious premolars or molars, planed to be restored with either class I, or class II restorations in 18 subjects (aged 18-25 yr., mean 21.5 yr.). The teeth were isolated with opaque black rubber dam and soft caries were removed. Then, the cavity was prepared with the airotor until the subject felt pain. The cavity was etched with 35% phosphoric acid for 10s. In group I, the cavity was filled with 20% lidocaine with 1:1,000 epinephrine. An iontophoretic device (Dentaphore-II model 611D, Life-tech, Inc.USA) was used with current 0.12–0.2 mA, 2 min., pain assessment was done. In group II, the experiments were performed exactly the same as group I, excepted distilled water was delivered with iontophoresis and pain sensation were assessed for 10 min. Pulpal blood flow (PBF) was recorded with a laser Doppler flowmeter (Periflux4001) before and after iontophoresis. The pain sensations induced by drilling, probing and air blast were assessed on 100 mm Visual analogue scale (VAS) before and after the treatments
Results: In group I (n=17), the PBF and mean VAS scores obtained at 2, 4, 6, 8, 10 min from all test stimuli were significantly decreased (P<0.05, 1-way RM ANOVA) after iontophoresis of lidocaine with epinephrine. In 16 teeth, the pulpal anesthesia was completely achieved within 0-10 min. In group II, distilled water iontophoresis produced no significant effect on the pain obtained from all stimuli (p>0.05, 1-way RM ANOVA on rank and Dunett’s test).
Conclusions: Iontophoretic application of 20% lidocaine with 1:1,000 epinephrine in carious human dentin could completely generate pulpal anesthesia.