IADR Abstract Archives
Clinical and Radiographic Comparison of Bovine Derived Xenograft versus Collagenated Xenograft.
Objectives: The purpose of the present study was to compare the clinical and radiographic effectiveness of a bovine derived xenograft (BDX) versus collagenated xenograft application in the treatment of intrabony periodontal defects of advanced chronic periodontitis patients.
Methods: Twenty advanced chronic periodontitis patients with the mean age of 45.25±9.82 who had radiographic intrabony defects with an associated probing depth (PD) of ≥5 mm and an intrabony component of ≥3 mm were included in the present study. A total of 108 intrabony defects were treated. While 55 of these defects were surgically treated with BDX (1st group), the other 53 were treated with collagenated xenograft (2nd group). Prior to and 12 months after surgery, plaque and sulcus bleeding indices, PD, marginal recession, relative attachment, probing bone and radiographic bone levels were recorded.
Results: Healing was uneventful in all cases. At 12 months postoperatively, intragroup comparisons for all evaluated clinical and radiographic parameters revealed statistically significant differences compared to baseline ( p<0.05). Considering the deepest site of the defects, group 1 and 2 showed a mean PD reduction of 3,05±0,78 mm and 3,35±0,62 mm, attachment gain of 2,36±0,58 mm and 2,58±0,86 mm, recession of 0,69±0,55mm and 0,76±0,64 mm, clinical bone gain of 2,13±0,66 mm and 2,19±0,95 mm and radiographic bone gain of 1,82±0,92 mm and 2,23±0,69 mm, respectively. Intergroup group comparisons for all parameters were insignificant (p>0.05).
Conclusions: Within the limits of this study, it can be concluded that both BDX and collagenated xenograft treatments lead to significantly favourable clinical improvements in intrabony periodontal defects compared to baseline. No statistically significant differences in any of the investigated parameters were observed between the two groups.
Methods: Twenty advanced chronic periodontitis patients with the mean age of 45.25±9.82 who had radiographic intrabony defects with an associated probing depth (PD) of ≥5 mm and an intrabony component of ≥3 mm were included in the present study. A total of 108 intrabony defects were treated. While 55 of these defects were surgically treated with BDX (1st group), the other 53 were treated with collagenated xenograft (2nd group). Prior to and 12 months after surgery, plaque and sulcus bleeding indices, PD, marginal recession, relative attachment, probing bone and radiographic bone levels were recorded.
Results: Healing was uneventful in all cases. At 12 months postoperatively, intragroup comparisons for all evaluated clinical and radiographic parameters revealed statistically significant differences compared to baseline ( p<0.05). Considering the deepest site of the defects, group 1 and 2 showed a mean PD reduction of 3,05±0,78 mm and 3,35±0,62 mm, attachment gain of 2,36±0,58 mm and 2,58±0,86 mm, recession of 0,69±0,55mm and 0,76±0,64 mm, clinical bone gain of 2,13±0,66 mm and 2,19±0,95 mm and radiographic bone gain of 1,82±0,92 mm and 2,23±0,69 mm, respectively. Intergroup group comparisons for all parameters were insignificant (p>0.05).
Conclusions: Within the limits of this study, it can be concluded that both BDX and collagenated xenograft treatments lead to significantly favourable clinical improvements in intrabony periodontal defects compared to baseline. No statistically significant differences in any of the investigated parameters were observed between the two groups.