Effect of Platelet Rich Fibrin on the Treatment of Gingival Recessions

Objectives: The objective of this randomized, parallel and controlled study was to assess the clinical effectiveness of platelet rich fibrin (PRF) in combination with coronally advanced flap (CAF) on defect coverage, esthetics and patient satisfaction compared to CAF alone for the treatment of Miller Class I multiple buccal recessions.
Methods: A total of 20 patients (10 females and 10males) with 49 Miller Class I multiple recessions ≥3 mm were included and divided into two groups, CAF+PRF and CAF. At baseline and 6 months after the surgery, plaque and gingival indices, probing depth, clinical attachment level, recession height (RH), keratinized tissue height, gingival thickness (GT), and mean and complete defect coverage were evaluated. Patient satisfaction, root coverage esthetic score were also assessed.
Results: Baseline RH in CAF+PRF and CAF alone groups was 3.36±0.34 mm and 3.2±0.26 mm, respectively. Intragroup comparisons revealed statistically significant differences at 6 months compared to baseline data for all parameters (p<0.05). GT increased from 0.78±0.06 mm to 1.31±0.07 mm in CAF+PRF group, and from 0.73±0.07 mm to 0.8±0.08 mm in CAF alone group. Mean defect coverage was 74.63 % (RH reduction: 2.51±0.33 mm) in CAF + PRF group, and 79.02 % (RH reduction: 2.5±0.53 mm) in CAF alone group with no statistically significant difference between the groups.
Conclusions: Both techniques were successfull in the treatment of Miller Class I gingival recessions. Tissue thickness significantly increased with the use of PRF graft in CAF+PRF group.