IADR Abstract Archives
A Comparative Clinical Evaluation of Titanium Prepared Platelet Rich Fibrin and Subepithelial Connective Tissue Graft for Management of Multiple Gingival Recession Defects
Objectives: A novel platelet-rich product, titanium-prepared platelet-rich fibrin (T-PRF), is based on the hypothesis that titanium is more effective at activating platelets than the silica activators used with glass tubes in platelet-rich fibrin. In our previous studies, we established that the fibrin carpet formed with titanium had a firmer network structure, and longer resorption time in the tissue than the fibrin carpet formed with glass. There has been no study to date comparing the effectiveness and predictability of T-PRF with that of the gold standard subepithelial connective tissue graft (CTG) for root coverage. The purpose of this randomized clinical trial was to compare these different autogenous graft materials (T-PRF& CTG) for the management of Miller Class I/II multiple adjacent gingival recessions.
Methods: 34 patients were referred to our clinic with a total of 104 Miller Class I/II gingival recessions represented that exposed root surfaces showed abrasion defects, indicating toothbrushing trauma as the causative factor. The brushing techniques were improved and recessions were randomly treated with T-PRF (52 teeth) or CTG (52 teeth) and modified tunnel technique. The following clinical measurements were taken before the surgery and at 1 month, 3 months and 6 months follow-up examination: probing depth (PD), clinical attachment level (CAL), amount of keratinized tissue (KT), and recession depth (RD). Also Visual Analog Scale, healing index were evaluated.
Results: After 6 months, mean root coverage was 91.08% and 88.66% in the T-PRF and CTG groups, respectively. Furthermore, the mean amount of KT increased by 1.33 mm and 0.95 mm in the T-PRF and CTG groups, respectively.
Conclusions: Within the limits of this study, the results demonstrated that T-PRF membrane is safe and effective in a treatment of Miller Class I/II gingival recession defects. T-PRF may present an alternative to CTG without a requirement for additional surgery.
Methods: 34 patients were referred to our clinic with a total of 104 Miller Class I/II gingival recessions represented that exposed root surfaces showed abrasion defects, indicating toothbrushing trauma as the causative factor. The brushing techniques were improved and recessions were randomly treated with T-PRF (52 teeth) or CTG (52 teeth) and modified tunnel technique. The following clinical measurements were taken before the surgery and at 1 month, 3 months and 6 months follow-up examination: probing depth (PD), clinical attachment level (CAL), amount of keratinized tissue (KT), and recession depth (RD). Also Visual Analog Scale, healing index were evaluated.
Results: After 6 months, mean root coverage was 91.08% and 88.66% in the T-PRF and CTG groups, respectively. Furthermore, the mean amount of KT increased by 1.33 mm and 0.95 mm in the T-PRF and CTG groups, respectively.
Conclusions: Within the limits of this study, the results demonstrated that T-PRF membrane is safe and effective in a treatment of Miller Class I/II gingival recession defects. T-PRF may present an alternative to CTG without a requirement for additional surgery.