IADR Abstract Archives

In-vitro Remineralisation of Glass Ionomer Cements

Objective: Glass ionomer cements (GICs) can be considered as source of calcium and phosphorus which, under favourable conditions may form apatite. This inherent potential to remineralise is another advantageous feature distinguishing the GICs from the composites and amalgam restorations. The objective of this study was to evaluate ability of GICs to biomineralise in vitro with and without addition of the remineralising agent, hydroxyapatite (HAp), in physiological conditions.

Method: A series of glasses based on 4.5SiO2-3Al2O3-1.5P2O5-(5-x)CaO-xCaF2 system, where x=0,1,2,3,3.5,4 were synthesised with varying CaF2/CaO proportions. The powders were then mixed with poly-acrylic acid, water and HAp in different ratios at specific powder to liquid ratios. The cement paste was transferred into Teflon mould, clamped, stored at 37oC for 1hr. The cement discs were immersed in 10ml of phosphate buffer saline at physiological pH for different durations, 7,14,28,56 days. The samples were collected at certain time, dried, ground into a powder and further characterised using Magic Angle Spinning Nuclear Magnetic Resonance (MAS-NMR).

Result: The 31P MAS-NMR results used to monitor changes in apatitic phosphorus showed that added HAp as remineralising agent was partially consumed during the setting reaction. No apatite formation was detected in the cements without HAp. The 27Al MAS-NMR was used to follow the setting reaction on conversion of the four-coordinated aluminium Al(IV) from the glass to the six-coordinated aluminium Al(VI) crosslinking the polymer. The results indicated that proportion of Al(VI) after setting, in the cements with HAp added was slightly higher compared to the same compositions with no HAp. However, the abundance of Al(VI) was identical in the cements with 0% and 2% HAp after 28 days.

Conclusion: Addition of HAp to GICs as remineralising agent causes partial dissolution of apatite and consumption of the calcium ions in crosslinking the polymeric acid during the setting reaction.

Division: British Division Meeting
Meeting: 2013 British Division Meeting (Bath, England)
Location: Bath England
Year: 2013
Final Presentation ID: 139
Abstract Category|Abstract Category(s): Scientific Groups
Authors
  • Albeshti, Rawan  ( Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, , England )
  • Karpukhina, Natalia  ( Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, N/A, England )
  • Bushby, Andy  ( School of Engineering and Materials Sciences, Queen Mary University of London, London, , England )
  • SESSION INFORMATION
    Oral Session
    Glasses
    09/10/2013