IADR Abstract Archives
Effectiveness of a Bioactive Glass With Strontium for Acid-Induced Demineralization
Objectives: Various novel materials and agents have been investigated in the in-vitro environment to evaluate their effectiveness prior to clinical evaluation. The aim of this in-vitro study was to evaluate the effectiveness of strontium Bioglass to inhibit acid induced demineralization through Immersion study and XRD analysis.
Methods: BG in the system (SiO2–P2O5–CaO–SrO–Na2O) were prepared using a melt–quench route. 100% of Ca was replaced by strontium on a molar basis in order to maintain the structure of the silicate glass matrix. Tris buffer (pH 7.3) and Acetic acid (pH 4.5) were used for the immersion studies at different time points (1h, 2h, 4h, 6h, 8h, 24h, 1 wk) and analysed through pH study and XRD analysis.
Results: BG was immersed in 0.1M Acetic acid (pH 4.5) for specific time periods (1h, 2h, 4h, 6h, 8h, 24h, 1wk). A pronounced rise in the pH has been observed for one week which was 5.45 pH. A rise in the pH is an indicator of strontium and fluorapatite formation which was confirmed through XRD analysis.
Conclusions: The observed results revealed that Strontium Bioglass is effective to inhibit acid induced demineralization. Strontium can be used as a marker to differentiate between the apatite formation formed by the breakdown of the Bioactiveglass and the other factors in the process of remineralization of the tooth.
Methods: BG in the system (SiO2–P2O5–CaO–SrO–Na2O) were prepared using a melt–quench route. 100% of Ca was replaced by strontium on a molar basis in order to maintain the structure of the silicate glass matrix. Tris buffer (pH 7.3) and Acetic acid (pH 4.5) were used for the immersion studies at different time points (1h, 2h, 4h, 6h, 8h, 24h, 1 wk) and analysed through pH study and XRD analysis.
Results: BG was immersed in 0.1M Acetic acid (pH 4.5) for specific time periods (1h, 2h, 4h, 6h, 8h, 24h, 1wk). A pronounced rise in the pH has been observed for one week which was 5.45 pH. A rise in the pH is an indicator of strontium and fluorapatite formation which was confirmed through XRD analysis.
Conclusions: The observed results revealed that Strontium Bioglass is effective to inhibit acid induced demineralization. Strontium can be used as a marker to differentiate between the apatite formation formed by the breakdown of the Bioactiveglass and the other factors in the process of remineralization of the tooth.