IADR Abstract Archives
Bioactivity Analysis of Novel Fluoride Releasing Bioactive Glass Based Dental Restorative Composites.
Objectives: Dental restorative materials that release calcium, phosphate and fluoride ions helps in remineralisation and can contribute to the prevention of secondary caries, which is one of the main reasons for failure of contemporary dental restorations. The aim of this study is to develop a novel bioactive glass based dental composite with better remineralisation properties.
Methods: Two Bioactive Glasses (BAG4, BAG6) containing SiO2-P2O5-CaO-CaF2-Na2O-K2O-MgO-SrO-ZnO prepared via the melt quench route at 1400C. The Network Connectivity was calculated as 2.43, 2.62 and Refractive Index are 1.56,1.55 respectively. Glass powder added in the resin matrix composed of BisEMA, UDMA and TEGDMA and light cured for 20s. Samples were stored at 37C in different Artificial Saliva pH=7 and pH=4 (AS7 and AS4) for varying time intervals. All synthesized samples were characterized using Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Radio-opacity analysed by aluminium step-wedge, pH measurement, Release of bioactive ions recorded by ICP-OES technique and release of Fluoride evaluated by ISE studies.
Results: FTIR spectra and XRD patterns of both bioactive composites showed characteristic peaks for the formation of apatite both in AS4 and AS7 which increases with time. Degree of conversion of dental composite ranges between 70-81%. Radio-opacity of the glass found to be 2.22 and 1.84. All samples showed an increase in pH with time. It has been observed that BAG4 release more fluoride than BAG6. ICP results showed the release of bioactive ions i.e Ca and P within 24h for the formation of apatite which relates with XRD and FTIR results.
Conclusions: These novel BAG composite has shown promising results and can be used successfully in the field of conservative dentistry for repair, remineralisation, and reconstruction. However, further investigations are required for clinical application.
Methods: Two Bioactive Glasses (BAG4, BAG6) containing SiO2-P2O5-CaO-CaF2-Na2O-K2O-MgO-SrO-ZnO prepared via the melt quench route at 1400C. The Network Connectivity was calculated as 2.43, 2.62 and Refractive Index are 1.56,1.55 respectively. Glass powder added in the resin matrix composed of BisEMA, UDMA and TEGDMA and light cured for 20s. Samples were stored at 37C in different Artificial Saliva pH=7 and pH=4 (AS7 and AS4) for varying time intervals. All synthesized samples were characterized using Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Radio-opacity analysed by aluminium step-wedge, pH measurement, Release of bioactive ions recorded by ICP-OES technique and release of Fluoride evaluated by ISE studies.
Results: FTIR spectra and XRD patterns of both bioactive composites showed characteristic peaks for the formation of apatite both in AS4 and AS7 which increases with time. Degree of conversion of dental composite ranges between 70-81%. Radio-opacity of the glass found to be 2.22 and 1.84. All samples showed an increase in pH with time. It has been observed that BAG4 release more fluoride than BAG6. ICP results showed the release of bioactive ions i.e Ca and P within 24h for the formation of apatite which relates with XRD and FTIR results.
Conclusions: These novel BAG composite has shown promising results and can be used successfully in the field of conservative dentistry for repair, remineralisation, and reconstruction. However, further investigations are required for clinical application.