Effect of Radiotherapy on Oral Malodour- Pilot Study

Objective: This pilot study looks to assess whether the Halimeter (Interscan corporation, model number RH17E, serial numer H13900) can detect variation in volatile sulphur gas readings as a result of radiotherapy to the oral cavity. The study also looks to assess if such changes are associated with oral malodour. Methods: It is well known that most head and neck cancer patients smoke and drink alcohol.To control their potential effect on the halimeter reading we compared head and neck cancer patients to lung cancer patients receiving radiotherapy.Another control group with patients suffering from cancer, but not receiving radiotherapy was also used. Breath samples were taken from all three groups using the halimeter. A baseline reading was taken and then weekly readings noted for the head and neck patients until treatment was complete. Results: The halimeter readings in patients with head and neck cancer increased during the first weeks of radiotherapy. Conclusion: Radiotherapy to the oral cavity is associated with dry mouth and mucositis. In this group of patients, oral malodour is a common occurrence. By ascertaining the timing of the malodour with cumulative radiotherapy an objective method for mouthwash use might be established. The halimeter is able to detect changes in oral volatile sulphur gas readings within one week of starting radiotherapy.