POF is classified within the benign neoplasia from the craneomaxillofacial territory. It is of low occurrence and has a greater impact in the female sex between 20 and 40 years of age. In the mandible, appears in the back section, premolars and molars; meanwhile, in the maxilla it hurts the front zone. 150 cases were published during the last decade, however in other study, from 91.178 cases only 23 cases where diagnosed as POF. The next case is a 12 years old girl, with facial asymmetry and increase volume in her right mandibular zone. Extraoral exam showed rubiculate and local heat. The intraoral exam shows an occupied vestibule at the 4.6 piece level, spontaneous gingivorragia and gingival inflammation of the respective hemi mandible. Palpation is swelling and painful with a soft consistency, slightly fluctuating. Diagnostic hypothesis was pericoronaritis and vestibular abscess. The complementary exams: Rx retroalveolar to 4.6 piece and panoramic showed a compatible image with an osteolitic process (4.6) and a cyst lesion (4.7). An urgent drilling piece (4.6) was made leaving it without seal. An incisional biopsy was taken from its histopathological analysis, which diagnosed was a connective epithelial hyperplasia. However, a second surgery was programmed for the excisional biopsy the same analysis. Diagnostic was POF. Clinical controls were made 7 and 30 days after and 3 to 9 months. X rays controls were made 30 days, 6 months after and also will be done it 12 months. The patient has not reported pain and there are no clinical signs. There is an asymmetry in the right mandible, for this reason, she was sent to the specialist. The POF is a local aggressive lesion. There are some cases reported in writing to fewer association with other pathologies. Never the less there is a chance of a syndrome given the semiology of the case.