IADR Abstract Archives

Oral candidal carriage in asymptomatic patients

Objective:  Interest in the association between oral cancer risk and promotion of mucosal dysplasia with presence of Candida continues. These yeast can be detected quantitatively in salivary samples by means of culture. The purpose of this prospective cross-sectional clinical study was to ascertain the prevalence and degree of carriage of Candida in the oral cavities of a non-cancer population, with reference to a range of parameters affecting the oral environment, such as smoking status, as well as dental and periodontal health.

Method:  Oral rinse samples were collected from 203 patients attending the Royal Dental Hospital of Melbourne and analysed for the presence, degree of colonisation, and pattern of Candidal species, phenotypically identified as albicans and non-albicans species.

Result:  Candidal carriage was found in 98/203 patients (48.3%) and of these, 83 (84.7%) patients carried C. albicans. There was no statistical difference when comparing gender, age, or presence of a removable prostheses. Significant variation was found in the prevalence and degree of Candida colonisation in patients who were current or past smokers, and patients with active carious lesions were found to be 3 times more likely to carry Candida than those with no active carious lesions. 

Conclusion: These results indicate the degree of variation in oral yeast carriage that exists in asymptomatic, non-oral cancer patients and indicates a potential correlation between smoking, caries and oral yeast colonisation.

Division: Australian/New Zealand Division Meeting
Meeting: 2014 Australian/New Zealand Division Meeting (Brisbane, Australia)
Location: Brisbane, Australia
Year: 2014
Final Presentation ID:
Abstract Category|Abstract Category(s): Scientific Groups
Authors
  • Mun, Michelle  ( Melbourne Dental School, University of Melbourne, Carlton, , Australia )
  • Al-nuaimi, Ali  ( Melbourne Dental School, Oral Health CRC, University of Melbourne, Carlton, , Australia )
  • Yap, Tami  ( Melbourne Dental School, Oral Health CRC, University of Melbourne, Melbourne, , Australia )
  • Mccullough, Michael  ( Melbourne Dental School, University of Melbourne, Melbourne, , Australia )
  • SESSION INFORMATION
    Oral
    Oral Medicine and Pathology