Molar-Incisor Hypomineralisation In 9-Year-Old Monozygotic Twin In Ile-Ife

Introduction: Molar Incisor Hypomineralisation (MIH) is defined as a hypomineralisation of systemic origin of one to four permanent first molars frequently associated with affected incisors. The prevalence of MIH in different studies ranges from 3.5-25% and differ between regions. Several aetiological factors are suggested as possible causes. METHOD: Case Description: This is a case report of a set of 9-year old female monozygotic twins who were diagnosed to have MIH following a school health visit. RESULT: There was history of severe diarrhea in the first 2 years of life and prolong use of amoxicillin in both twins. Intra oral examination showed they had MIH involving all the first permanent molars, and one incisor (12 for one and 32 for the other). Caries was found on 16 and 36 of one twin and 36 of the other. Neither parents of the twins had MIH. The carious lesions were restored with GIC, and fluoride gel application was done. Conclusion: The case suggests that the possible aetiology of MIH may be due to systemic factors such as the use of amoxicillin. There were little pointers to the role of genetics in the aetiology of MIH in this monozygote twins. There is however the need for further investigation into the role of genetics or heredity in the aetiology of MIH .