Implant dentistry has become a cornerstone dental treatment modality. The variations in the dental implant systems available result in different complications that reflect on the long-term success rate of these implants. Objectives: The purpose of this prospective study was to evaluate the clinical success rate of the Tiolox® dental implant system over a period of three years after loading. Methods: Fifty-seven patients (31 females and 26 males) were rehabilitated with (148) Tiolox® dental implants (maxilla n=86, mandible n=62). Single-tooth prostheses (n=52), fixed partial prostheses (n=23), implant/tooth-supported prostheses (n= 15), cantilever fixed prostheses (n=7) and full arch prostheses (n=3). Results: the overall success rate for the implant after three years of service was (89.7%). The success rate of the 12 mm length implant was (91.8%) while that for the 10 mm implants was (86.3%). Fifteen implants failed (maxilla n=8, mandible n=7). Three implants failed before loading (maxilla n=2, mandible n=1). Nine implants failed during the first year after loading (maxilla n=5, mandible n=4). Three implants failed during the second year (maxilla n=1, mandible n=2). No implants failed in the third year. Conclusions: Prostheses supported by the Tiolox® dental implant system represent a reliable treatment for partially edentulous patients after 3 years.